Journal of Preventive Medicine and Public Health

Original Article

Development and Validation of a Novel Generic Health-related Quality of Life Instrument With 20 Items (HINT-20): Min-Woo Jo, Hyeon-Jeong Lee, Soo Young Kim, Seon-Ha Kim, Hyejung Chang, Jeonghoon Ahn, Minsu Ock; J Prev Med Public Health. 2017;50(1):38-59. Published online January 10, 2017; DOI: https://doi.org/10.3961/jpmph.16.081

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Objectives
Few attempts have been made to develop a generic health-related quality of life (HRQoL) instrument and to examine its validity and reliability in Korea. We aimed to do this in our present study.
Methods
After a literature review of existing generic HRQoL instruments, a focus group discussion, in-depth interviews, and expert consultations, we selected 30 tentative items for a new HRQoL measure. These items were evaluated by assessing their ceiling effects, difficulty, and redundancy in the first survey. To validate the HRQoL instrument that was developed, known-groups validity and convergent/discriminant validity were evaluated and its test-retest reliability was examined in the second survey.
Results
Of the 30 items originally assessed for the HRQoL instrument, four were excluded due to high ceiling effects and six were removed due to redundancy. We ultimately developed a HRQoL instrument with a reduced number of 20 items, known as the Health-related Quality of Life Instrument with 20 items (HINT-20), incorporating physical, mental, social, and positive health dimensions. The results of the HINT-20 for known-groups validity were poorer in women, the elderly, and those with a low income. For convergent/discriminant validity, the correlation coefficients of items (except vitality) in the physical health dimension with the physical component summary of the Short Form 36 version 2 (SF-36v2) were generally higher than the correlations of those items with the mental component summary of the SF-36v2, and vice versa. Regarding test-retest reliability, the intraclass correlation coefficient of the total HINT-20 score was 0.813 (p<0.001).
Conclusions
A novel generic HRQoL instrument, the HINT-20, was developed for the Korean general population and showed acceptable validity and reliability.

Summary

Citations

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A Review of the Types and Characteristics of Healthy Life Expectancy and Methodological Issues
Young-Eun Kim, Yoon-Sun Jung, Minsu Ock, Seok-Jun Yoon
Journal of Preventive Medicine and Public Health.2022; 55(1): 1. CrossRef
Health-Related Quality of Life (HRQOL) Instruments and Mobility: A Systematic Review
Natalia Hernández-Segura, Alba Marcos-Delgado, Arrate Pinto-Carral, Tania Fernández-Villa, Antonio J. Molina
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Meaning and Status of Health-related Quality of Life Recognized by Medical Professionals: a Qualitative Study
Jeehee Pyo, Minsu Ock, Bohyun Park, Nam-eun Kim, Eun Jeong Choi, Hyesook Park, Hyeong Sik Ahn
Journal of Korean Medical Science.2021;[Epub] CrossRef
Validity and reliability of the Health-Related Quality of Life Instrument with 8 Items (HINT-8) in Korean breast cancer patients
Juyoung Kim, Min-Woo Jo, Hyeon-Jeong Lee, Sei-Hyun Ahn, Byung Ho Son, Jong Won Lee, Sae Byul Lee
Osong Public Health and Research Perspectives.2021; 12(4): 254. CrossRef
Developing a comprehensive, culturally sensitive conceptual framework of health domains in Singapore
Julian Thumboo, Mandy Y. L. Ow, Elenore Judy B. Uy, Xiaohui Xin, Zi Ying Clarice Chan, Sharon C. Sung, Dianne Carrol Bautista, Yin Bun Cheung, Xiang Li
PLOS ONE.2018; 13(6): e0199881. CrossRef

English Abstract

Impact of an Early Hospital Arrival on Treatment Outcomes in Acute Ischemic Stroke Patients.: Young Dae Kwon, Sung Sang Yoon, Hyejung Chang; J Prev Med Public Health. 2007;40(2):130-136.; DOI: https://doi.org/10.3961/jpmph.2007.40.2.130

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Abstract PDF

OBJECTIVES
Recent educational efforts have concentrated on patient's early hospital arrival after symptom onset. The purpose of this study was to evaluate the time interval between symptom onset and hospital arrival and to investigate its relation with clinical outcomes for patients with acute ischemic stroke. METHODS: A prospective registry of patients with signs or symptoms of acute ischemic stroke, admitted to the OO Medical Center through emergency room, was established from September 2003 to December 2004. The interval betwee symptom onset and hospital arrival was recorded for each eligible patient and analyzed together with clinical characteristics, medication type, severity of neurologic deficits, and functional outcomes. RESULTS: Based on the data of 256 patients, the median interval between symptom onset and hospital arrival was 13 hours, and 22% of patients were admitted to the hospital within 3 hours after symptom onset. Patients of not-mild initial severity and functional status showed significant differences between arrival hours of 0-3 and later than 3 in terms of their functional outcomes on discharge. Logistic regression models also showed that arrival within 3 hours was a significant factor influencing functional outcome (OR=5.6; 95% CI=2.1, 15.0), in addition to patient's initial severity, old age, cardioembolism subtype, and referral to another hospital. CONCLUSIONS: The time interval between symptom onset and hospital arrival significantly influenced treatment outcome for patients with acute ischemic stroke, even after controlling for other significant clinical characteristics. The findings provided initiatives for early hospital arrival of patients and improvement of emergency medical system.

Summary

Citations

Citations to this article as recorded by

Computer Aided Diagnosis Applications for the Differential Diagnosis of Infarction: Apply on Brain CT Image
Hyong-Hu Park, Mun-Joo Cho, In-Chul Im, Jin-Soo Lee
Journal of the Korean Society of Radiology.2016; 10(8): 645. CrossRef
The Visiting Time of Acute Cerebral Stroke Patients in a City and Its Influencing Factors
英方
Nursing Science.2016; 05(04): 81. CrossRef
Stroke Education: Discrepancies among Factors Influencing Prehospital Delay and Stroke Knowledge
Yvonne TeuschI, Michael Brainin
International Journal of Stroke.2010; 5(3): 187. CrossRef
Notfall Schlaganfall
T. Steigleder
Notfall + Rettungsmedizin.2008; 11(3): 166. CrossRef

Original Articles

Burden of Disease in Korea: Years of Life Lost due to Premature Deaths.: Hyejung Chang, Jae Il Myoung, Youngsoo Shin; Korean J Prev Med. 2001;34(4):354-362.

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Abstract PDF: OBJECTIVES
The aim of this study was to estimate the burden of disease through an analysis of Years of Life Lost due to premature deaths, one component of the Disability-Adjusted Life Years (DALY). In addition, the cause of death statistics were adjusted to improve validity, and the results were compared with those of the Global Burden of Disease (GBD). METHODS: In closely following the approach taken in the original GBD study, most of the explicit assumptions and the value judgments were not changed. However, the statistics for some problematic concerns such as deaths of infants or those due to senility, were adjusted. Deaths, standard expected years of life lost (SEYLL), and potential years of life lost (PYLL) were computed using vital registration data compiled by the National Statistical Office. RESULTS: The burden for males is 1.8 and 2.3 times higher than that for females, according to SEYLL and PYLL, respectively. The proportions of deaths due to Group I, II, and III causes are 5.4%, 80.4%, and 14.3%, respectively, for PYLL, but in a major shift from Group II to III they are 6.3%, 66.2%, and 27.5%, respectively, for SEYLL. The proportion of Group III causes in Korea, 27.5%, is extremely high when compared to 10.1% for the world, 7.6% for developed countries, and 10.7% for developing countries. CONCLUSIONS: Estimation results showed that the total burden due to premature deaths is smaller than that for the entire world but larger than that for developed countries. The disease structure of Korea has changed to resemble that of developed countries. Also, an overly large portion of the total burden in Korea stems from injuries arising from car accidents.; Summary

Measuring the Burden of Major Cancers due to Premature Death in Korea.: Seok Jun Yoon, Yong Ik Kim, Chang Yup Kim, Hyejung Chang; Korean J Prev Med. 2000;33(2):231-238.

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Abstract PDF: OBJECTIVE
To estimate the burden of diseases in Korea especially caused by major cancers using the YLL(years of life lost due to premature death) measurement. METHODS: First, we determined the parameters: such as age-specific standard life expectancy, age on death, sex, cause of death by analyzing the national death certificate data and life table collected during 1996 provided by the National Statistical Office. Secondly, we estimated the age group-specific YLL by employing standard expected years of life lost(SEYLL). Thirdly, final burden of disease due to premature death was estimated by using YLLs measurement which developed by global burden of disease study group. RESULTS: The burden of premature death by cancer for male was attributed mainly to liver cancer(514.5 person-year), stomach cancer(436.4 person-year), and lung cancer(367.7 person-year). Each of these cancers was responsible for the loss of over 100 person-year based on our YLL measurement. The burden of premature death by cancer for female was attributed mainly to liver cancer(135.1 person-year), stomach cancer(252.1 person-year), and lung cancer(121.8 person-year). Each of these cancers was responsible for the loss of over 100 person year based on our YLL measurement. CONCLUSION: We found the YLL method employed in this study was appropriate to quantify the burden of premature death. Thereby, it would provide a rational bases to plan a national health policy regarding premature death caused by cancer.; Summary

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